This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate.
Tablet capping and lamination.
Lamination is also caused by the presence of a large amount of fines in the granulations.
This is the problem faced in the formulation of the granules.
Before rectifying be sure it is lamination where is the problem surface of tablet below the top layer or bottom of tablet.
Better understand the tablet capping lamination phenomenon.
Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process.
First lamination is caused by air being trapped in the tablet especially among the granules or particles.
Using acetaminophen containing formulations we examined the potential use of a compaction simulator as a material sparing tool to predict capping occurrence under commercial.
Abstract air entrapment efficiency of the powders is one of the main factors leading to occurrence of capping or lamination tendency of tablets manufactured from the directly compressible powder blends.
Capping or lamination is an unsolved common problem in tablet manufacturing.
Root causes of lamination.
Fines are small dust particles which.
Lamination is whenever tablet is breaking or separating anywhere rather than top if is separating from top it is capping.